MSC 2032964A
CAS No. 1124381-43-6
MSC 2032964A ( MSC-2032964A; MSC2032964A; MSC 2032964A )
Catalog No. M27999 CAS No. 1124381-43-6
MSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 240 | Get Quote |
|
10MG | 381 | Get Quote |
|
25MG | 620 | Get Quote |
|
50MG | 883 | Get Quote |
|
100MG | 1215 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameMSC 2032964A
-
NoteResearch use only, not for human use.
-
Brief DescriptionMSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.
-
DescriptionMSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.
-
SynonymsMSC-2032964A; MSC2032964A; MSC 2032964A
-
PathwayOthers
-
TargetOther Targets
-
RecptorCalcium Channel
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1124381-43-6
-
Formula Weight362.3
-
Molecular FormulaC16H13F3N6O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESFC(F)(F)c1cc(NC2CC2)n2nc(NC(=O)c3cccnc3)nc2c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Samy MEROUEH, et al. Preparation of pyrazolyl acylpyrazolines for the treatment of pain. WO2020061303A1
molnova catalog
related products
-
Calcium trinatrium d...
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication).
-
5'-UMP disodium salt
Uridine 5′-monophosphate disodium salt has been used to study the effect of pyrimidine synthesis inhibitor, 5-azacytidine, on cholesterol and lipid metabolism.
-
LW6
LW6 is a novel HIF-1 inhibitor.