MSC 2032964A

CAS No. 1124381-43-6

MSC 2032964A ( MSC-2032964A; MSC2032964A; MSC 2032964A )

Catalog No. M27999 CAS No. 1124381-43-6

MSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 240 Get Quote
10MG 381 Get Quote
25MG 620 Get Quote
50MG 883 Get Quote
100MG 1215 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    MSC 2032964A
  • Note
    Research use only, not for human use.
  • Brief Description
    MSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.
  • Description
    MSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.
  • Synonyms
    MSC-2032964A; MSC2032964A; MSC 2032964A
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Calcium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1124381-43-6
  • Formula Weight
    362.3
  • Molecular Formula
    C16H13F3N6O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    FC(F)(F)c1cc(NC2CC2)n2nc(NC(=O)c3cccnc3)nc2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Samy MEROUEH, et al. Preparation of pyrazolyl acylpyrazolines for the treatment of pain. WO2020061303A1
molnova catalog
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